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The Lyon-Saint Exupйry is located 16 miles (25 km) east of Lyons. The airport Web site is in French, but even if your French is rusty as a stale croissant (what!?!), you might find the following accessible and useful:
Taxis are available just outside the arrivals hall. Fare to the center will be around 200 francs ($32) during the day and 300 francs ($48) at night. The trip takes about 30 minutes.
There is a bus service to the city center and the two train stations leaving every 20 minutes from 5 A.M. to 11 P.M. The fare is about 48 francs ($8) and travel time is about 35 minutes. From the central bus stops it's a short taxi ride to other destinations within Lyons.
There is also a bus service to Grenoble from the airport. Travel time is a little over one hour, with a fare of about 130 francs ($21).
Avis, Budget, Europcar, Hertz, Sixt and some local firms are represented at the airport on Level 1 in the central hall. They also have offices in the central city.
World Airport Information Main Page
Adapted from How to Get Out of the Airport